Chromosome maps of legumes

GENETIC RESOURCES, CHROMOSOME ENGINEERING, AND CROP IMPROVEMENT Grain Legumes

Building chromosome-wide LD maps

SUMMARY BMapBuilder builds maps of pairwise linkage disequilibrium (LD) in either two or three dimensions. The optimized resolution allows for graphical display of LD for single nucleotide polymorphisms (SNPs) in a whole chromosome. AVAILABILITY The program is coded in Java, which runs on all relevant operating systems, including Windows, Mac and Unix/Linux, and is available from http://bios....

Linkage Variation and Chromosome Maps.

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Isochore chromosome maps of the human genome.

The human genome is a mosaic of isochores, which are long DNA segments (z.Gt;300 kbp) relatively homogeneous in G+C. Human isochores were first identified by density-gradient ultracentrifugation of bulk DNA, and differ in important features, e.g. genes are found predominantly in the GC-richest isochores. Here, we use a reliable segmentation method to partition the longest contigs in the human g...

Statistical model of intra-chromosome contact maps

The statistical properties of intra-chromosome maps obtained by a genome-wide chromosome conformation capture method (Hi-C) are described in the framework of the hierarchical crumpling model of heteropolymer chain with quenched disorder in the primary sequence. We conjecture that the observed Hi-C maps are statistical averages over many different ways of hierarchical genome folding, and show th...